PTGIS

prostaglandin I2 synthase

Details

HGNC: HGNC:9603
GeneCards: PTGIS
NCBI: 5740
Ensembl: ENSG00000124212
UniProt: Q16647
OMIM: 601699
UCSC: uc002xut.4
VEGA: OTTHUMG00000033077
ENA: None

Alias Symbols: PGIS, CYP8A1
Previous Symbols: None
Alias Names: "cytochrome P450, family 8, subfamily A, polypeptide 1", "prostacyclin synthase"
Previous Names: "prostaglandin I2 (prostacyclin) synthase"

Associated Studies

Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome

2025 | Boutin, Thibaud; Bretherick, Andrew D.; Dibble, Joshua J.; Ewaoluwagbemiga, Esther; Northwood, Emma; Samms, Gemma L.; Vitart, Veronique; Almelid, Øyvind; Baker, Tom; Clyde, Malgorzata; Connolly, Anne; Garcia, Diana; Kerr, Shona M.; Tripp, Claire; Wolfe, Jareth C.; Goold, Jackie; Hoyes, Gemma; Leary, Sian; McGrath, Simon J.; Milton, Julie; Redshaw, Anna; Wilson, Jim M.; Baxter, Helen; Boobyer, Danielle; Dransfield, Claire; Lamirel, Daphne; Lewis, Isabel; Muirhead, Nina; Ponting, Ella; Shepherd, Charles; Turner, Alice; Baby, Sumy V.; Beentjes, Sjoerd; Ireland, John; Khamseh, Ava; McDowall, Ewan; Perry, David; Slaughter, Joshua; Abner, Erik; Boer, Cindy G.; Finer, Sarah; Haapaniemi, Hele; Ollila, Hanna M.; Pollack, Beth; Rosmalen, Judith; Romppanen, Erika; Saafi, Sirine; Saxena, Richa; Sinnott-Armstrong, Nasa; Tervi, Anniina; Urpa, Lea; Valliere, Jesse; van Heel, David A.; Chowdhury, Sonya; Devereux-Cooke, Andy; Ponting, Chris P.

Associated cohorts
Phenotype: ME/CFS, Post-exertional malaise (PEM)