Temporal Dynamics of the Plasma Proteomic Landscape Reveals Maladaptation in ME/CFS Following Exertion

Authors: Germain, Arnaud; Glass, Katherine A.; Eckert, Melissa A.; Giloteaux, Ludovic; Hanson, Maureen R.

Molecular & Cellular Proteomics, Dec 2025

View article | Discussion on S4ME


Cohorts in this study

Phenotype: ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC), Post-exertional malaise (PEM)

AHSG, BAGE3, CBLN4, CRPPA, DBI, KLHL41, MICB, MICU3, MMP8, MYBPC1, MYL3, NCAM1, NDRG3, OXLD1, PRPS2, SERPINB1, SHISA2, SOSTDC1, SUSD3, TNFSF4, YJEFN3

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Notes

Proteins from Results section, specifically from "Key Proteins Provide Novel Insights into ME/CFS Muscle and Brain Biology" and "Correlation of Protein Levels With Clinical Parameters in Patients With ME/CFS".